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The role of Vitamin D in beta-cell function
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PhD title: .
Graduate student: Sue Lynn Lau
Performers: Members of the Diabetes & Transcription Factors Lab Group
Synopsis: Every PhD begins in the dark, but it takes only a few bright sparks to kindle the flame of discovery...
The crucial role of sunlight exposure as the most important source of vitamin D in humans is highlighted. Vitamin D is newly recognised to be involved in the function of many organ systems, including the beta cells of the endocrine pancreas. These cells make insulin in response to glucose stimulation.
Initially, the beta cells are in an unstimulated state, with minimal activity. At the arrival of the sugar plum fairy (symbolising glucose), the cells are able to sense the presence of glucose through the enzyme glucokinase. When glucose enters the cells through glut 2 transporters (marshmallow feeding), it is metabolised to produce the energy molecule, ATP. Through a number of steps, this leads to a rise in positive charge inside the cell, which ultimately triggers the export of insulin-storing granules by a process known as exocytosis (depicted here by the blowing of bubbles). Normal insulin secretion requires the coordinated function of beta cells via intercellular connections and communications as they work in concert.
We are investigating whether vitamin D has an effect in improving beta-cell function and increasing insulin secretion... are they "walking on sunshine"?? |
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79926
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| Time:
04:47 |
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Selah Sue - Valerie
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live in AB, support 'the dø' |
Views:
22282
38
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| Time:
03:19 |
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Maria Sue Chapman Memorial Service - News Coverage
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News Channel 2's coverage of the Maria Sue Chapman memorial service. Steven Curtis Chapman and his wife both speak in the clip.
Matt Redman is one playing guitar and singing.
Check out my memorial video I made about Maria:
http://youtube.com/watch?v=ay1vgulzR8I |
Views:
167063
121
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| Time:
01:59 |
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People & Blogs |
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Betty White as Sue Ann Nivens
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Betty White, along with her "MTMS" co-stars and writers, talks about her character Sue Ann Nivens. |
Views:
14161
46
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| Time:
05:30 |
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Sue Foley - Blues in D Natural / Queen Bee
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Two songs from the early 90's (1992?).
Born and raised in Ottawa Canada, Sue Foley hails from a large, music-loving family. In her early years, she sang with her father, who loved to play Celtic folk songs while her brothers were in bands hammering out the hard rock covers of the 1970s. Her love of the Rolling Stones and other blues rock bands found Sue checking song writing credits on the albums, where the names like Willie Dixon, McKinley Morganfield and Chuck Berry were found, leading to her study and appreciation of the blues. For her thirteenth birthday, she received her first guitar - "it was my saving grace," she says, and locked herself in her room until she learned how to play. At age sixteen she was gigging around Ottawa clubs, at eighteen she left home for Vancouver, British Columbia, with nothing more than a small suitcase and her guitar.
Foley sent a demo tape of herself to Clifford Antone's label (Antone's Records) in 1990. Impressed, the record label arranged an audition for the guitarist. She moved to Austin, Texas and soon signed a recording contract with Antone's.
By now she has been writing and playing for over twenty years, has recorded ten albums, for both Antone's Records and Shanachie Records and has spent many years on the road as a bandleader, lead vocalist, guitarist and manager of her own band. In addition to her own touring, she has also shared the stage with other blues musicians, such as B. B. King, Buddy Guy and John Lee Hooker.
More info:
http://www.suefoley.com/ |
Views:
17343
49
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| Time:
06:56 |
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Johnny Cash - A Boy Named Sue
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Live from the dansih television broadcastingstudios of DR(Danmarks Radio) back in 1971 |
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43853
81
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| Time:
03:28 |
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Dion & The Belmonts - Runaround Sue
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82022
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| Time:
02:35 |
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The Life of a Mary Sue
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writen and sung by Skittle Sama.
I only put the lyrics into the vid. Nothing else is mine! |
Views:
35383
631
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| Time:
03:38 |
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negaraku..(jangan sue saye.. saye takde duit..)
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Negaraku Tanah Tumpah... |
Views:
678956
1844
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| Time:
05:45 |
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Johnny Cash - A Boy Named Sue
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Tom Jones' show 1970 |
Views:
63037
136
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| Time:
03:38 |
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Talk Sex-Rough Anal Sex
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Sue Johanson warns a caller of the dangers of rough anal sex! |
Views:
467209
651
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| Time:
02:16 |
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Comedy |
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Nathan Lane & Faith Prince Sue Me Guys and Dolls
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Nathan Lane and Faith Prince sing "Sue Me" from Guys and Dolls revival on Tonight Show |
Views:
114930
289
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| Time:
03:18 |
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